Sp1 Transcription Factor

**Definition:** Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.

**Tree numbers:** - D12.776.260.522.750.249 - D12.776.930.375.750.249

**Synonyms:** - Specificity Protein 1 Transcription Factor - Transcription Factor, Sp1