Lymphoma, Large-Cell, Immunoblastic

**Definition:** Malignant lymphoma characterized by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (LYMPHOMA, T-CELL, PERIPHERAL) recorded in both the United States and Japan.

**Tree numbers:** - C04.557.386.480.493 - C15.604.515.569.480.493 - C20.683.515.761.480.487

**Synonyms:** - Immunoblastoma - Sarcoma, Immunoblastic - Immunoblastic Lymphosarcoma, Diffuse - Large-Cell Immunoblastic Lymphoma - Lymphoma, Immunoblastic, Large Cell - Lymphoma, Large Cell, Immunoblastic - Immunoblastic Large-Cell Lymphoma - Lymphoma, Immunoblastic, Large-Cell