Neurofibromatosis 2

**Definition:** An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.

**Tree numbers:** - C04.557.465.625.650.595.610.500 - C04.557.580.600.580.590.655 - C04.557.580.600.610.595.610.500 - C04.700.631.655 - C09.218.807.800.675.500 - C09.647.675.500 - C10.292.225.750.500 - C10.292.910.600.500 - C10.562.600.750 - C10.574.500.549.700 - C16.320.400.560.700 - C16.320.700.633.655

**Synonyms:** - Neurofibromatosis, Acoustic, Bilateral - Neurofibromatosis, Central, NF2 - Neurofibromatosis, Central, NF 2 - Neurofibromatosis, Type 2 - NF2 (Neurofibromatosis 2) - Neurofibromatosis, Central NF2 - Central Neurofibromatosis - Neurofibromatosis, central type - Neurofibromatosis II - Neurofibromatosis Type II - Neurofibromatosis Type 2 - Bilateral Acoustic Neurofibromatosis - Neurofibromatosis, Type II