Mucopolysaccharidosis II

**Definition:** Systemic lysosomal storage disease marked by progressive physical deterioration and caused by a deficiency of L-sulfoiduronate sulfatase. This disease differs from MUCOPOLYSACCHARIDOSIS I by slower progression, lack of corneal clouding, and X-linked rather than autosomal recessive inheritance. The mild form produces near-normal intelligence and life span. The severe form usually causes death by age 15.

**Tree numbers:** - C10.597.606.360.455.750 - C16.320.322.500.750 - C16.320.400.525.750 - C16.320.565.202.715.645 - C16.320.565.595.600.645 - C17.300.550.575.645 - C18.452.648.202.715.645 - C18.452.648.595.600.645

**Synonyms:** - Mucopolysaccharidosis 2 - Gargoylism, Hunter Syndrome - Hunter Syndrome Gargoylism - Mucopolysaccharidosis Type 2 - Mucopolysaccharidosis Type II - Hunter's Syndrome - Hunter Syndrome