Amyloid beta-Protein Precursor

**Definition:** A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.

**Tree numbers:** - D12.776.049.407.249 - D12.776.543.039 - D12.776.811.050 - D12.776.815.468.500

**Synonyms:** - beta-Amyloid Protein Precursor - Amyloid A4 Protein Precursor - Protease Nexin 2 - Protease Nexin II - Amyloid beta Precursor Protein - Amyloid Protein Precursor