Talin

**Definition:** A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.

**Tree numbers:** - D12.776.220.985

**Synonyms:** - Band 2 Protein