Proto-Oncogene Proteins c-jun

**Definition:** Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.

**Tree numbers:** - D12.776.260.108.820 - D12.776.624.664.700.182 - D12.776.660.763 - D12.776.930.127.820

**Synonyms:** - c-jun Proteins - fos-Associated Protein p39 - jun Proto-Oncogene Product p39 - Proto-Oncogene Proteins jun - c-fos-Associated Protein p39 - p39 c-jun - p39(c-jun) - Proto-Oncogene Products c-jun - jun Proto-Oncogene Proteins