D016898Level 8
Interferon-alpha
**Definition:** One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
**Tree numbers:** - D12.644.276.374.440.890.250 - D12.776.467.374.440.890.250 - D23.529.374.440.890.250
**Synonyms:** - Interferon, alpha - alpha-Interferon - Interferon, Lymphoblast - Interferon Alfa - Interferon, Lymphoblastoid - Interferon, Leukocyte
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