Clarithromycin

**Definition:** A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.

**Tree numbers:** - D02.540.576.500.992.100

**Synonyms:** - 6-O-Methylerythromycin