D017293Level 5
Protein S
**Definition:** The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.
**Tree numbers:** - D09.400.430.920 - D12.776.124.670 - D12.776.395.642 - D23.113.725
**Synonyms:** - Protein S, Vitamin K-Dependent - Vitamin K-Dependent Protein S - Cofactor Protein S
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