Cyclic AMP Response Element-Binding Protein

**Definition:** A protein that has been shown to function as a calcium-regulated transcription factor as well as a substrate for depolarization-activated CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. This protein functions to integrate both calcium and cAMP signals.

**Tree numbers:** - D12.776.260.108.184 - D12.776.930.127.184

**Synonyms:** - cAMP Response Element-Binding Protein - CREB Protein - Cyclic AMP-Responsive DNA-Binding Protein - DNA-Binding Protein, Cyclic AMP-Responsive