Kallmann Syndrome

**Definition:** A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.

**Tree numbers:** - C12.050.351.875.253.096.750 - C12.200.706.316.096.750 - C12.800.316.096.750 - C16.131.939.316.096.750 - C16.320.467 - C19.391.119.096.750 - C19.391.482.600

**Synonyms:** - Anosmic Hypogonadism - Anosmic Idiopathic Hypogonadotropic Hypogonadism - Dysplasia Olfactogenitalis of De Morsier - Hypogonadotropic Hypogonadism and Anosmia - Hypogonadotropic Hypogonadism-Anosmia Syndrome - Kallmann's Syndrome