Receptors, Somatostatin

**Definition:** Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Activated somatostatin receptors on pituitary cells inhibit the release of growth hormone; those on endocrine and gastrointestinal cells regulate the absorption and utilization of nutrients; and those on neurons mediate somatostatin's role as a neurotransmitter.

**Tree numbers:** - D12.776.543.750.695.850 - D12.776.543.750.720.600.760 - D12.776.543.750.750.555.760 - D12.776.543.750.750.580.720 - D12.776.543.750.750.700.800

**Synonyms:** - Somatostatin Receptor - Somatostatin Receptors - Receptors, Somatotropin Release Inhibiting Hormone - Receptors, SRIH - SRIH Receptors