Ki-1 Antigen

**Definition:** A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of the Ki-1 antigen in hematopoietic malignancies make it clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

**Tree numbers:** - D12.776.543.750.705.852.760.072 - D23.050.285.025 - D23.101.140.055

**Synonyms:** - Antigens, CD30 - Ber-H2 Antigen - Ber-H2 Antigens - Antigens, Ki-1 - Ki-1 Antigens - Tumor Necrosis Factor Receptor Superfamily, Member 8 - TNFRSF8 Receptor - CD30 Antigens - CD30 Antigen