Receptors, GABA

**Definition:** Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.

**Tree numbers:** - D12.776.543.750.720.200.300

**Synonyms:** - GABA Receptors - gamma-Aminobutyric Acid Receptor - gamma-Aminobutyric Acid Receptors - Receptors, gamma-Aminobutyric Acid - GABA Receptor