Signal Recognition Particle

**Definition:** A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).

**Tree numbers:** - D12.776.157.725.500.750.800 - D12.776.664.962.500.750.800

**Synonyms:** - SRP (Signal Recognition Particle)