Receptors, Adrenergic, alpha-2

**Definition:** A subclass of alpha-adrenergic receptors found on both presynaptic and postsynaptic membranes where they signal through Gi-Go G-PROTEINS. While postsynaptic alpha-2 receptors play a traditional role in mediating the effects of ADRENERGIC AGONISTS, the subset of alpha-2 receptors found on presynaptic membranes signal the feedback inhibition of NEUROTRANSMITTER release.

**Tree numbers:** - D12.776.543.750.670.300.300.300.200 - D12.776.543.750.695.150.300.300.725 - D12.776.543.750.720.330.300.300.200

**Synonyms:** - alpha 2 Adrenergic Receptors - Receptor, Adrenergic, alpha-2 - Adrenergic Receptor, alpha-2 - Adrenergic alpha-2 Receptors - Receptors, alpha-2 Adrenergic - alpha-2 Adrenergic Receptors