Leukocyte-Adhesion Deficiency Syndrome

**Definition:** Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.

**Tree numbers:** - C16.320.798.719 - C20.673.795.719

**Synonyms:** - Deficiency Syndrome, Leukocyte-Adhesion