PrPC Proteins

**Definition:** Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.

**Tree numbers:** - D12.776.785.340.500

**Synonyms:** - Scrapie Amyloid Precursor Protein - PrP-sen - Cp33-35, Scrapie - Cp 33-35