Interleukin-12

**Definition:** A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.

**Tree numbers:** - D12.644.276.374.465.512 - D12.776.467.374.465.512 - D23.529.374.465.512

**Synonyms:** - Interleukin 12 - Natural Killer Cell Stimulatory Factor - IL12 - IL 12 - IL-12 p70 - Interleukin-12 p70 - IL-12 - Cytotoxic Lymphocyte Maturation Factor