Hexamethonium

**Definition:** A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

**Tree numbers:** - D02.092.877.250.592.400 - D02.675.276.558.592.500

**Synonyms:** - Hexonium