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D018921Level 5

Leukostasis

**Definition:** Abnormal intravascular leukocyte aggregation and clumping often seen in leukemia patients. The brain and lungs are the two most commonly affected organs. This acute syndrome requires aggressive cytoreductive modalities including chemotherapy and/or leukophoresis. It is differentiated from LEUKEMIC INFILTRATION which is a neoplastic process where leukemic cells invade organs.

**Tree numbers:** - C15.378.553.560

**Synonyms:** - Leukostasis Syndrome

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