GTP-Binding Protein alpha Subunits, Gi-Go

**Definition:** A family of heterotrimeric GTP-binding protein alpha subunits that were originally identified by their ability to inhibit ADENYLYL CYCLASES. Members of this family can couple to beta and gamma G-protein subunits that activate POTASSIUM CHANNELS. The Gi-Go part of the name is also spelled Gi/Go.

**Tree numbers:** - D08.811.277.040.330.300.200.100.200 - D12.776.157.325.332.100.200 - D12.776.476.338.200.100.200 - D12.776.543.325.100.200

**Synonyms:** - G-Protein, Gi-Go alpha Family - G-Protein, Gi-Go Subunits - Gi-Go G-Proteins