Genes, bcl-2

**Definition:** The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.

**Tree numbers:** - G05.360.340.024.340.375.500.791.150

**Synonyms:** - bcl-2 Genes