Cytochrome P-450 CYP2E1

**Definition:** An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.

**Tree numbers:** - D08.244.453.491.375 - D08.811.682.662.582.338 - D08.811.682.690.708.170.450.375 - D12.776.422.220.453.491.375

**Synonyms:** - CYPIIE1 - N-Nitrosodimethylamine Demethylase - Cytochrome P-450 (ALC) - Cytochrome P-450-J - 4-Nitrophenol-2-Hydroxylase - Dimethylnitrosamine N-Demethylase - Cytochrome P450 2E1 - CYP2E1 - CYP 2E1 - CYP IIE1 - Cytochrome P-450 IIE1