Cytochrome P-450 CYP11B2

**Definition:** A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.

**Tree numbers:** - D08.244.453.484.500 - D08.244.453.915.050 - D08.811.682.690.708.170.425.500 - D08.811.682.690.708.170.915.050 - D12.776.422.220.453.484.500 - D12.776.422.220.453.915.050

**Synonyms:** - CYP11B2 - P450c11AS - Steroid 18-Hydroxylase - Aldosterone Synthase - Aldosterone Synthase Cytochrome P-450 - Aldosynthase - Cytochrome P450Aldo - CYP 11B2 - Cytochrome P450 11B2 - Cytochrome P-450c11AS