Mice, Inbred MRL lpr

**Definition:** A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.

**Tree numbers:** - B01.050.050.199.520.520.555 - B01.050.150.900.649.313.992.635.505.500.400.555

**Synonyms:** - Mouse, Inbred MRL lpr - Mice, MRL lpr - Mouse, MRL lpr