D019812Level 6
Heparan Sulfate Proteoglycans
**Definition:** Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)
**Tree numbers:** - D09.400.430.930.350 - D09.698.373.425.500 - D09.698.735.400 - D12.776.395.650.350
**Synonyms:** - Heparan Sulfate Proteoglycan - HSPG - Proteoheparan Sulfate
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