Proto-Oncogene Proteins c-met

**Definition:** Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.

**Tree numbers:** - D08.811.913.696.620.682.725.400.075 - D12.776.476.568.400.075 - D12.776.543.750.630.186 - D12.776.543.750.750.400.100 - D12.776.624.664.700.186

**Synonyms:** - MET Receptor Tyrosine Kinase - c-Met Receptor Tyrosine Kinase - Receptor, Hepatocyte Growth Factor - Receptor, Scatter Factor - Scatter Factor Receptor - Receptor, HGF - HGF Receptor - Hepatocyte Growth Factor Receptor - c-met Proteins - MET Proto-Oncogene, Receptor Tyrosine Kinase - met Proto-Oncogene Proteins