Somatostatin-Secreting Cells

**Definition:** Endocrine cells found throughout the GASTROINTESTINAL TRACT and in islets of the PANCREAS. D cells secrete SOMATOSTATIN that acts in both an endocrine and paracrine manner. Somatostatin acts on a variety of tissues including the PITUITARY GLAND; gastrointestinal tract; pancreas; and KIDNEY by inhibiting the release of hormones, such as GROWTH HORMONE; GASTRIN; INSULIN; and RENIN.

**Tree numbers:** - A03.556.875.875.440.854 - A03.734.414.793 - A06.300.414.793 - A06.390.825 - A10.615.550.291.825 - A11.382.625.950 - A11.436.294.950

**Synonyms:** - D Cells - Somatostatin Cells - delta Cells