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D019869Level 7

Phosphatidylinositol 3-Kinases

**Definition:** Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.

**Tree numbers:** - D08.811.913.696.620.500 - D12.776.476.556

**Synonyms:** - Phosphoinositide 3 Kinases - PI3-Kinase - Phosphatidylinositol-3-OH Kinase - Phosphoinositide 3-Hydroxykinase - PI 3-Kinase - PI-3 Kinase - PtdIns 3-Kinase - PI3 Kinases - PI-3K - PtdIns 3-Kinases

GET/api/v1/systems/mesh/nodes/D019869
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