GAP-43 Protein

**Definition:** A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.

**Tree numbers:** - D09.400.430.890.400 - D12.776.395.550.400 - D12.776.543.550.400 - D12.776.631.400

**Synonyms:** - Phosphoprotein B-50 - GAP-43 - Neuromodulin - Phosphoprotein F1 - Phosphoprotein pp46 - B-50 Protein - GAP43 Protein - Nerve Growth Cone Membrane Protein GAP-43 - Growth-Associated Protein 43