Activated Protein C Resistance

**Definition:** A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.

**Tree numbers:** - C15.378.100.100.037 - C15.378.100.141.036 - C15.378.925.050 - C16.320.099.037

**Synonyms:** - APC Resistance