ATP Binding Cassette Transporter, Subfamily B, Member 1

**Definition:** A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

**Tree numbers:** - D09.400.430.890.020.400.153 - D12.776.157.530.100.075.063 - D12.776.157.530.450.074.500.500.250.125 - D12.776.395.550.020.400.153 - D12.776.543.550.192.400.153 - D12.776.543.585.100.200.125 - D12.776.543.585.450.074.500.500.250.125

**Synonyms:** - ABCB1 Protein - CD243 Antigen - ATP Binding Cassette Transporter, Sub-Family B, Member 1 - P-Glycoprotein - MDR1 Protein - Multidrug Resistance Protein 1 - ATP-Binding Cassette, Sub-Family B, Member 1 - PGY-1 Protein