Caspase 1

**Definition:** A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.

**Tree numbers:** - D08.811.277.656.262.500.126.550.100 - D08.811.277.656.300.200.126.550.100 - D12.776.476.075.405.550.100

**Synonyms:** - CASP1 Caspase - ICE Protease - IL-1 beta Convertase - IL-1 beta-Converting Enzyme - IL1BC Enzyme - Interleukin-1 Converting Enzyme - Interleukin-1beta Converting Enzyme