Limbic Encephalitis

**Definition:** A paraneoplastic syndrome marked by degeneration of neurons in the LIMBIC SYSTEM. Clinical features include HALLUCINATIONS, loss of EPISODIC MEMORY; ANOSMIA; AGEUSIA; TEMPORAL LOBE EPILEPSY; DEMENTIA; and affective disturbance (depression). Circulating anti-neuronal antibodies (e.g., anti-Hu; anti-Yo; anti-Ri; and anti-Ma2) and small cell lung carcinomas or testicular carcinoma are frequently associated with this syndrome.

**Tree numbers:** - C01.207.245.700 - C04.588.614.550.450 - C04.730.856.437 - C10.228.140.430.525 - C10.228.228.245.700 - C10.574.781.550 - C10.586.250.525

**Synonyms:** - Paraneoplastic Limbic Encephalitis - Encephalitis, Limbic