I-kappa B Proteins

**Definition:** A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.

**Tree numbers:** - D12.644.360.365 - D12.776.260.420 - D12.776.476.381 - D12.776.930.326

**Synonyms:** - I-kappa B - I kappa B - IkB DNA-Binding Proteins