ADP-Ribosylation Factors

**Definition:** MONOMERIC GTP-BINDING PROTEINS that were initially recognized as allosteric activators of the MONO(ADP-RIBOSE) TRANSFERASE of the CHOLERA TOXIN catalytic subunit. They are involved in vesicle trafficking and activation of PHOSPHOLIPASE D. This enzyme was formerly listed as EC 3.6.1.47

**Tree numbers:** - D08.811.277.040.330.300.400.100 - D12.776.157.325.515.100 - D12.776.476.338.400.100

**Synonyms:** - ADP-Ribosylation Factor - ARF Protein Cofactor