D020735Level 7
Guanine Nucleotide-Releasing Factor 2
**Definition:** A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.
**Tree numbers:** - D12.644.360.325.300.300 - D12.776.476.325.300.300
**Synonyms:** - GRF2 Protein, Mammalian - Guanine Nucleotide Exchange Factor C3G - GRF2 - GRF2 Protein - GRF-2 - C3G Protein - RAP1GRF1
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