Calcium Channels, L-Type

**Definition:** Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and non-excitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.

**Tree numbers:** - D12.776.157.530.400.150.400 - D12.776.543.550.450.150.400 - D12.776.543.585.400.150.400

**Synonyms:** - L-Type Voltage-Dependent Calcium Channel - L-Type Calcium Channels - Long-Lasting Calcium Channel - Long-Lasting Calcium Channels - L-Type Calcium Channel - L-Type Voltage-Dependent Calcium Channels - L-Type VDCC