Cathepsin C

**Definition:** A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE.

**Tree numbers:** - D08.811.277.656.224.130 - D08.811.277.656.262.186 - D08.811.277.656.350.350.100

**Synonyms:** - Dipeptidyl Aminopeptidase I - Dipeptidyl Peptidase I - Dipeptidyl Transferase