Diabetes Insipidus, Neurogenic

**Definition:** A genetic or acquired polyuric disorder caused by a deficiency of VASOPRESSINS secreted by the NEUROHYPOPHYSIS. Clinical signs include the excretion of large volumes of dilute URINE; HYPERNATREMIA; THIRST; and polydipsia. Etiologies include HEAD TRAUMA; surgeries and diseases involving the HYPOTHALAMUS and the PITUITARY GLAND. This disorder may also be caused by mutations of genes such as ARVP encoding vasopressin and its corresponding neurophysin (NEUROPHYSINS).

**Tree numbers:** - C12.050.351.968.419.135.750 - C12.200.777.419.135.750 - C12.950.419.135.750 - C19.700.159.750

**Synonyms:** - Central Diabetes Insipidus - Diabetes Insipidus Cranial Type - Diabetes Insipidus Primary Central - Diabetes Insipidus Secondary To Vasopressin Deficiency - Diabetes Insipidus, Central - Diabetes Insipidus, Cranial Type - Diabetes Insipidus, Neurohypophyseal - Diabetes Insipidus, Neurohypophyseal Type - Diabetes Insipidus, Pituitary - Diabetes Insipidus, Primary Central - Neurogenic Diabetes Insipidus - Neurohypophyseal Diabetes Insipidus - Pituitary Diabetes Insipidus - Vasopressin Defective Diabetes Insipidus - Vasopressin Deficiency