Chromosomes, Artificial, Human

**Definition:** DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, required for successful replication, propagation to and maintainance in progeny human cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.

**Tree numbers:** - A11.284.187.178.190.117 - A11.284.187.520.190.117 - A11.284.187.520.300.117 - G05.360.162.178.190.117 - G05.360.162.520.190.117 - G05.360.162.520.300.117 - G05.360.337.249.190.117

**Synonyms:** - Chromosomes, Human Artificial - Human Artificial Chromosomes - Artificial Chromosomes, Human - HAC (Chromosome) - HACs (Chromosomes)