CD40 Ligand

**Definition:** A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.

**Tree numbers:** - D09.400.430.890.185 - D12.644.276.374.750.124 - D12.776.395.550.185 - D12.776.467.374.750.124 - D12.776.543.550.198 - D23.529.374.750.124

**Synonyms:** - T-B Cell Activating Molecule - TNF Superfamily, Member 5 - Tumor Necrosis Factor Ligand Superfamily Member 5 - CD154 Antigens - gp39 Antigen, T-Cell - CD40L - Antigens, CD154 - CD154 Antigen - Antigen, CD154