AT-Hook Motifs

**Definition:** DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amino acids centered on the invariant tripeptide glycine-arginine-proline. They act to fasten the protein to an AT RICH SEQUENCE in the DNA.

**Tree numbers:** - G02.111.570.820.709.275.500.050

**Synonyms:** - AT Hooks - AT Hook Motif