Carboxypeptidase B2

**Definition:** A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.

**Tree numbers:** - D08.811.277.656.350.245.125 - D08.811.277.656.350.555.225 - D08.811.277.656.675.555.225 - D08.811.277.656.837.092

**Synonyms:** - Arginine Carboxypeptidase - Carboxypeptidase R - Carboxypeptidase B2, Plasma - Thrombin-Activatable Fibrinolysis Inhibitor - Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) - Carboxypeptidase U