Heterogeneous-Nuclear Ribonucleoprotein K

**Definition:** A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.

**Tree numbers:** - D12.776.157.725.500.313.500 - D12.776.157.725.813.750.500 - D12.776.260.268 - D12.776.664.962.500.313.500 - D12.776.664.962.813.750.500

**Synonyms:** - hnRNP K