Transcription Factors, General

**Definition:** Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be localized to distinct sequence and structural motifs within the DNA they are considered non-specific with regard to the specific gene being transcribed.

**Tree numbers:** - D12.776.260.775 - D12.776.930.930

**Synonyms:** - General Transcription Factors