Receptors, Eph Family

**Definition:** A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development.

**Tree numbers:** - D08.811.913.696.620.682.725.400.850 - D12.776.476.568.400.850 - D12.776.543.750.630.500

**Synonyms:** - Eph Receptor Tyrosine Kinase - Eph Family Receptors - Eph Receptors - Ephrin Receptors