Luteinizing Hormone, beta Subunit

**Definition:** The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

**Tree numbers:** - D06.472.699.322.576.463.500 - D06.472.699.631.525.343.463.500 - D12.644.548.691.525.343.463.500

**Synonyms:** - LH, beta Subunit - Luteinizing Hormone, beta Polypeptide Chain - Lutropin-beta - ICSH, beta Subunit - Luteinizing Hormone, beta Chain - Lutropin, beta Subunit - LH-beta